阿西替尼
中文同義詞:N-甲基-2-((3-((1E)-2-(吡啶-2-基)乙烯)-1H-吲唑-6-基)硫)甲酰胺
英文名稱:Axitinib
英文同義詞:AXITINIB;Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-;N-METHYL-2-{[3-((E)-2-PYRIDIN-2-YLVINYL)-1H-INDAZOL-6-YL]SULFANYL}BENZAMIDE;N-Methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide;AVERMECTINB;Axitinib for research;AG 013736;N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide
CAS號: 319460-85-0
分子式:C22H18N4OS
分子量:386.47
用途：阿西替尼可阻止對腫瘤生長和轉移起作用的某些被稱為激酶的蛋白發揮作用。
阿西替尼是一種小分子酪氨酸激酶抑制劑，對多個靶點有效，包括VEGF受體1,2和3。 
包裝：按客戶需求
銷售價格：650/g

Product Name:     Axitinib    

Synonyms:     AXITINIB;Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-;N-METHYL-2-{[3-((E)-2-PYRIDIN-2-YLVINYL)-1H-INDAZOL-6-YL]SULFANYL}BENZAMIDE;N-Methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide;AVERMECTINB;Axitinib for research;AG 013736;N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide    

CAS:     319460-85-0    

MF:     C22H18N4OS    

MW:     386.47    

Product Categories:     All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Protein Kinase Inhibitors and Activators;Pfizer compounds

Chemical Properties     Off-White Solid    

Assay 99%

Usage     A tyrosine kinase inhibitor; used in cancer therapy.    Axitinib (AG-013736) is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM, respectively.    

Packing  1kg /foli bag